Pathologic 2 Twelve days against the plague

You arrive as the son of the local healer, find him dead, and take his place. From there the clock never stops: each of the 12 days has its own events, and the town visibly changes as the plague spreads through it. Time is the real resource. You plan a day like a route on a map, weighing whether to visit a patient, chase a lead, or just find food before nightfall, and you will not manage everything. Some tasks go undone, some people go untreated, and doing nothing is a choice with consequences too. The game tells you plainly that you cannot save everyone, then keeps handing you people worth saving.

Your body is a problem to manage: hunger, thirst, exhaustion and infection all press in, and they only get worse as the days pass. You need resources, and how you get them is up to you. Trade with the local kids, loot bins and houses, beg, steal, or mug someone in an alley. Combat is short, clumsy and vicious, and most people, yourself included, would rather hand over a wallet than die for it. You can also make medicine, treat the sick, and perform autopsies to learn how the plague kills. One moment you are performing surgery on a man with a knife in his belly; the next you are deciding whether his organs are better off in your pocket.