Games like Substrate: Emergence

If Substrate: Emergence scratched a replayable and relaxing itch for you, keep reading. Start with these games when you are ready.

Cheaper than Substrate: Emergence

Thrive

Thrive

Grow a microbe into a species, choosing every adaptation as your alien world changes around you.

92% of 1,726 Steam reviews are positivePlayers online now: 21$4.99
Gridworld

Gridworld

Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger…

85% of 238 Steam reviews are positivePlayers online now: 1$1.99
Cellings

Cellings

Cellings is a creative sandbox game taking place in an abstract procedural world full of various species.

95% of 37 Steam reviews are positive$7.99
Biosys Inc

Biosys Inc

Biosys Inc. is a biology simulator that takes you to a new planet where you will be responsible for the process of abiogenesis.

71% of 7 Steam reviews are positive$3.99
Microcosmum: survival of cells

Microcosmum: survival of cells

Grow your cells, absorb your rivals and take over the microscopic world, one drifting organism at a time.

80% of 1,119 Steam reviews are positivePlayers online now: 1$7.99
Cell HD: emergence

Cell HD: emergence

Based on a 3D version of mathematician John Conway's "Game of Life," the game puts the player in a biological world that is uncannily alive.

63% of 8 Steam reviews are positive$5.99
PHYSARUM: Slime Mold Simulator

PHYSARUM: Slime Mold Simulator

PHYSARUM is a sandbox simulation game. Simulate the real world slime mold Physarum polycephalum by generating millions of living particles.

90% of 21 Steam reviews are positive$5.99
evolution for beginners

evolution for beginners

Evolution For Beginners is an evolution simulation where you can create and cultivate your own species by only using evolutionary mechanics.

67% of 3 Steam reviews are positive$3.49
XenoBloom

XenoBloom

A calm creative experience where you guide the development of an alien ecosystem.

63% of 32 Steam reviews are positive$4.99
Simultree

Simultree

Simultree is a short incremental game about monitoring life simulations.

86% of 147 Steam reviews are positivePlayers online now: 2$6.99
Earthtongue

Earthtongue

Care for a miniature ecosystem in a strange world, exert limited influence to encourage the growth of different fungi and bugs and try to maintain…

90% of 153 Steam reviews are positive$4.99

Hidden gems like Substrate: Emergence

Planetary Life

Planetary Life

Terraform a barren world, tune its climate and watch the life you seed evolve across millennia, all at your own unhurried pace.

94% of 949 Steam reviews are positivePlayers online now: 17$11.99
Primordialis

Primordialis

Design a living creature from cells and send it into the deep, where every run rebuilds it from scratch.

93% of 1,025 Steam reviews are positivePlayers online now: 42$19.99
The Bibites: Digital Life

The Bibites: Digital Life

Digital life that actually evolves. Bibites are tiny creatures with neural network brains and genes of their own: set up a world, let natural…

96% of 229 Steam reviews are positivePlayers online now: 30$9.99
Simultree

Simultree

Simultree is a short incremental game about monitoring life simulations.

86% of 147 Steam reviews are positivePlayers online now: 2$6.99
Ecosystem

Ecosystem

Seed a simulated ocean with random creatures and watch evolution do the rest.

76% of 611 Steam reviews are positivePlayers online now: 4$19.99
Thrive

Thrive

Grow a microbe into a species, choosing every adaptation as your alien world changes around you.

92% of 1,726 Steam reviews are positivePlayers online now: 21$4.99
Lifecraft

Lifecraft

Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its…

81% of 141 Steam reviews are positive$22.99
Rogue AI Simulator

Rogue AI Simulator

Play as a Rogue Artificial Intelligence, in the sequel to the hit Flash game "I'm an Insane Rogue AI", played more than 4 million times!

82% of 368 Steam reviews are positive$11.99
The Sapling

The Sapling

Design creatures and plants, release them into one world, and watch what evolution does with your creations.

88% of 1,987 Steam reviews are positivePlayers online now: 53$17.99
Surviving the Abyss

Surviving the Abyss

Run a cold war cloning lab on the ocean floor, juggling oxygen, power and light while something waits beyond your pylons.

64% of 1,054 Steam reviews are positivePlayers online now: 5$19.99
Space Simulation Toolkit

Space Simulation Toolkit

Build tiny worlds from atoms, tweak their rules, and see what happens.

80% of 518 Steam reviews are positivePlayers online now: 17$17.77

Newest games like Substrate: Emergence

Mycelarium

Mycelarium

Flick your mycelium through the soil, tap hidden water and unlock strange mutations at your own pace.

82% of 839 Steam reviews are positivePlayers online now: 335$4.99
Honeycomb: The World Beyond

Honeycomb: The World Beyond

Scan strange plants, crossbreed creatures and raise a base on Sota7, a planet that hides a mystery worth your patience.

68% of 236 Steam reviews are positivePlayers online now: 23$29.99
Pathogenic

Pathogenic

You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your…

93% of 5,160 Steam reviews are positivePlayers online now: 655$9.99
Mycelium Conquest

Mycelium Conquest

A deep biological network automation game where you grow a living mycelial network across an alien planet.

75% of 12 Steam reviews are positive$9.99
Dead 4 Now: Bio-Weapon Simulator

Dead 4 Now: Bio-Weapon Simulator

Craft bio-weapons, master lethal science, and unleash global annihilation. Experiment. Fail. Adapt. Evolve. Repeat until humankind falls.

73% of 30 Steam reviews are positive$14.99
Simultree

Simultree

Simultree is a short incremental game about monitoring life simulations.

86% of 147 Steam reviews are positivePlayers online now: 2$6.99
Monster Lab Simulator

Monster Lab Simulator

Buy strange essences, raise adorable Fulus and grow a lab that turns cute creatures into a steady income.

71% of 524 Steam reviews are positivePlayers online now: 7$12.99
Cellchemist

Cellchemist

Solve carefully crafted puzzles and experiment with over 100 cells in this physics sandbox where every pixel is simulated.

89% of 47 Steam reviews are positiveFree
ANLIFE: Motion-Learning Life Evolution

ANLIFE: Motion-Learning Life Evolution

A relaxing evolution simulation where AI-driven block creatures move in unexpected ways.

83% of 168 Steam reviews are positivePlayers online now: 3$13.99
Adaptory

Adaptory

Deep in uncharted space, your expedition took a challenging turn when your ship crash-landed.

76% of 99 Steam reviews are positive$19.99
Strange Seed

Strange Seed

Eat DNA, grow new body parts and fight your way from forests to volcanoes as the build you design.

85% of 456 Steam reviews are positivePlayers online now: 15$14.99
Planetary Life

Planetary Life

Terraform a barren world, tune its climate and watch the life you seed evolve across millennia, all at your own unhurried pace.

94% of 949 Steam reviews are positivePlayers online now: 17$11.99