
Plague M.D.
Plague M.D. is a medieval medicine simulator. Become a quack doctor stuck in a backwater village in the 16th century.
If Pestis left you wanting something hand-drawn and dark, you have options. Start with these games when you are ready.
Plague M.D. is a medieval medicine simulator. Become a quack doctor stuck in a backwater village in the 16th century.
Hand-drawn, Dark
The plague spreads agony and fear in the small town of Wippra. As a plague doctor, you bring healing and relief wherever you can. But ignorance, superstition, and religious zeal make for a deadly threat in this retro medieval medical adventure!
Hand-drawn, Dark, Atmospheric
The city is drowning in Plague. Panic, hunger, and fear are tearing it apart. You are the last one who can change its fate: heal it, hold it back from collapse… or drive it to ruin with your own hands!
Hand-drawn, Dark, Atmospheric
In a world ravaged by plague, a lone plague doctor embarks on a journey to stop both the disease and a sinister order of knights controlling it. Dr. Plague is a stealth-adventure game that combines puzzle-solving, platforming, and ambient soundtracks.
Hand-drawn, Dark, Atmospheric
A plague is eating a strange town on the steppe, and you have 12 days to do something about it. Pathologic 2 is a hard, story-driven survival RPG about running out of time: treat the sick, trade with children, autopsy bodies, and decide who deserves your last loaf of bread. You will not save everyone. That is the point.
Hand-drawn, Dark, Atmospheric
You are Patient Zero's pathogen, and your job is to end human history. Plague Inc: Evolved is a tense strategy sim about spreading, mutating, and outsmarting cure labs, with 10 disease types, 23 scenarios, and endless custom plagues to try next.
Dark, Replayable
Step into the role of the Wunderdoktor, a traveling doctor whose daily work is to cure rare and exotic diseases. Explore a world full of quackery, ghosts and addictive potions.
Hand-drawn, Atmospheric, Scary
Stop a deadly plague in a medieval fantasy tale of swords and surgery! Unearth medical knowledge, prevent the town’s purge, or plot your own escape.
Dark, Minimalist, Replayable
Plague: London 1665 is an RPG with pixel art graphics set in 1665's during the Bubonic Plague outbreak in overcrowded and polluted London. As a body collector, graveyard keeper, and family provider, avoid the disease while clearing the streets. Will you survive the outbreak or become another victim?
Dark, Atmospheric, Replayable
A Plague Tale: Innocence follows Amicia and her little brother Hugo through 14th-century France while the Black Death spreads and the Inquisition hunts them. A dark, emotional story of two children surviving swarms of rats, told with striking visuals and a haunting soundtrack.
Dark, Atmospheric, Scary
A plague is coming to the mountain village of Grimshire, and you are its only farmer. Grow crops, raise animals, preserve food before it rots, and keep the whole village fed through the year. A farming sim where every harvest matters, and so does everyone you meet.
Dark, Atmospheric, Replayable
Play doctor or play plague. Bio Inc. Redemption is a biomedical strategy game where you either diagnose and save a dying patient or build the disease that kills them, one organ system at a time. Over 600 real conditions, tough real-time decisions, and a dark sense of humor.
Dark, Replayable

Plague M.D. is a medieval medicine simulator. Become a quack doctor stuck in a backwater village in the 16th century.

The plague spreads agony and fear in the small town of Wippra. As a plague doctor, you bring healing and relief wherever you can.

The city is drowning in Plague. Panic, hunger, and fear are tearing it apart.

In a world ravaged by plague, a lone plague doctor embarks on a journey to stop both the disease and a sinister order of knights controlling it. Dr.

Spread a pathogen across the globe, mutate it faster than humanity can fight back, and watch your strategy play out differently every run.

Step into the role of the Wunderdoktor, a traveling doctor whose daily work is to cure rare and exotic diseases.

Stop a deadly plague in a medieval fantasy tale of swords and surgery! Unearth medical knowledge, prevent the town’s purge, or plot your own escape.

Plague: London 1665 is an RPG with pixel art graphics set in 1665's during the Bubonic Plague outbreak in overcrowded and polluted London.

A plague is coming to the mountain village of Grimshire, and you are its only farmer.

Diagnose a dying patient or engineer the disease that takes them down, one organ system at a time.

Great Alchemist is a classic 3-in-a-row puzzle game.

Survive twelve days in a plague-stricken town, balancing resource management, desperate negotiations, and medical care.

A short medical simulation horror game with multiple endings where the imperfect are made HAPPY.

A plague is coming to the mountain village of Grimshire, and you are its only farmer.

Triage the infected, keep the budget alive and run an emergency room with friends while the apocalypse waits outside.

Craft, build and stay healthy in a sick open world, alone or with a friend, while a mysterious plague closes in.

A 1–4 player co-op horror game. Cleanse cursed lands, perform forbidden rituals, and survive a spreading plague. Fear is not scripted.

Diagnose the dying, rule a plague town by decree, and bend time itself to fix what went wrong.

A dark medieval survival RPG where your village is your lifeline.

Lovecraftian Doctor Simulator. Diagnose patients by analyzing unsettling symptoms and treat them using your Book of Medicine.

The plague spreads agony and fear in the small town of Wippra. As a plague doctor, you bring healing and relief wherever you can.

This game is a simulation of self-isolation. You need to support your family, not to lose your job and finally not to go crazy.

Diagnose patients, brew remedies from foraged ingredients, and slowly earn the trust of a skeptical little town.

The game will teach you how to stay at home, make trips to the store, use masks and various antiseptics. Buckwheat, toilet paper, masks, city pass..

No Emergency: Pestilence plunges players into the epicenter of a mysterious epidemic, where every arriving patient could be carrying a mutating…

A 1–4 player co-op horror game. Cleanse cursed lands, perform forbidden rituals, and survive a spreading plague. Fear is not scripted.

A short medical simulation horror game with multiple endings where the imperfect are made HAPPY.

A dark medieval survival RPG where your village is your lifeline.

Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their…

The city is drowning in Plague. Panic, hunger, and fear are tearing it apart.

You are a slave. A collar with three lights hangs around your neck: each one fades and shocks you for mistakes or disobedience.

Diagnose the dying, rule a plague town by decree, and bend time itself to fix what went wrong.

Triage the infected, keep the budget alive and run an emergency room with friends while the apocalypse waits outside.

A plague is coming to the mountain village of Grimshire, and you are its only farmer.

Fable Hospital is a medieval hospital management simulator with a touch of fantasy and humor.

Step into the role of a doctor in the town of Stagmarch, where an otherworldly illness is mutating residents.