Games like Multicellular

If Multicellular left you wanting something cute and colorful, you have options. You might settle into these games easily.

Thrive
Start as the first spark of life on an alien planet and steer your species across billions of years. Build your microbe from real organelles, hunt or photosynthesise your way to survival, and watch rival species evolve against you. A calm, science-driven evolution sandbox where every run plays out differently.
Replayable
92% of 1,726 Steam reviews are positivePlayers online now: 21$4.99
Cellings
Cellings is a creative sandbox game taking place in an abstract procedural world full of various species. Experience the full evolution of cells across 3 generations, compete with other species, and explore breathtaking worlds.
Cute, Colorful, Replayable
95% of 37 Steam reviews are positive$7.99
SPORE™
Grow one species from a tidepool cell to a starfaring civilization, shaping its bodies, huts, trucks and starships along the way. Five short stages keep changing what you do, and your earlier choices follow you forward. It is bright, silly and easy to pick up.
Cute, Colorful, Replayable
92% of 67,348 Steam reviews are positivePlayers online now: 751$19.99
Microcosmum: survival of cells
A real-time strategy about microorganisms, played out in a calm, colorful microscopic world. Send your cells drifting across the level, absorb weaker neighbors and grow, and outmaneuver every rival on the board. Simple to learn, oddly soothing, and surprisingly tactical once the field fills up.
Cute, Colorful
80% of 1,119 Steam reviews are positivePlayers online now: 1$7.99
Lifecraft
Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its functions to a fully fledged system! Assemble, breathe, eat, fight threats, produce energy, grow, anything is possible!
Colorful, Replayable
81% of 141 Steam reviews are positive$22.99
The Sapling
Design your own plants, algae, fungi and animals, then set them loose in a world together. Add random mutations and watch evolution fill every niche, or shape the planet yourself, ice ages included. A calm, creative ecosystem toy from solo developer Wessel Stoop.
Cute, Replayable
88% of 1,974 Steam reviews are positivePlayers online now: 53$17.99
Planetary Life
Shape a dead planet into a living world. Move mountains and seas, tune the climate, then seed cells and watch them evolve into plants, animals and strange chimera of your making. Guide every step or sit back and see what 50,000 years cook up. A calm, colorful sandbox for anyone who ever wanted to play at being a very patient god.
Cute, Colorful, Replayable
94% of 948 Steam reviews are positivePlayers online now: 17$11.99
Cell to Singularity - Evolution Never Ends
Tap from lifeless rock to humans, dinosaurs, Mars and beyond. Cell to Singularity turns 4.5 billion years of evolution into a relaxed cosmic clicker, where every click earns Entropy and unlocks the next fish, lizard, mammal or machine, with real science notes along the way.
89% of 28,541 Steam reviews are positivePlayers online now: 5,045Free
EvoLife
Create and evolve your own digital lifeforms! Watch or interact as your creations adapt and thrive in a world governed by the laws of physics. Download now and start your own evolutionary journey!
Replayable
83% of 30 Steam reviews are positive$9.99
Everything is Crab: The Animal Evolution Roguelite
A cute, fast action roguelite about evolution: eat, grow and pick from 125+ animal abilities to build a new chimera every run. Hunt, flee or charm your way through a living ecosystem, then get Darwin'd and start again. Wings on a crab are allowed. Science weeps.
Cute, Colorful, Replayable
77% of 7,140 Steam reviews are positivePlayers online now: 238$9.99
Primordialis
Build a fish out of living cells, then send it into the primordial depths to fight for its life. Venom, electricity, jaws, whatever you can engineer from 60+ cell types. A brutal physics roguelike where your creations are the weapon, and death takes them all back.
Replayable, Chaotic, Surreal
93% of 1,023 Steam reviews are positivePlayers online now: 39$19.99
Species: Artificial Life, Real Evolution
Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.
Replayable
73% of 975 Steam reviews are positivePlayers online now: 1$19.99

Cheaper than Multicellular

Thrive

Grow a microbe into a species, choosing every adaptation as your alien world changes around you.

$4.99

Cellings

Cellings is a creative sandbox game taking place in an abstract procedural world full of various species.

$7.99

Microcosmum: survival of cells

Grow your cells, absorb your rivals and take over the microscopic world, one drifting organism at a time.

$7.99

Sparkle 2 Evo

Guide a tiny aquatic creature through a surreal deep, choosing what it eats and what it becomes.

$4.99

Creature Crafter

Design creatures from body parts, watch them come to life, and explore open worlds with friends.

$7.99

Evolution Board Game

Predators lurk, food is scarce, you must adapt - or go extinct.

$5.99

Cell Dominion

Eat, Grow, Divide, Dominate! Survive a hostile microscopic ocean, evolve powerful genes, build organelles and lead your colony into online battles.

$3.30

Cellfish

Collect food to evolve and fight for your life against enemy cells in this deep underwater, survivor-like, roguelite experience.

$4.99

Gridworld

Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger…

$1.99

Evolution of Species 2: Online

Welcome to the world of microscopic creatures! Help your creation evolve from an inconspicuous inhabitant of the microscopic depths into a unique…

$2.99

Simultree

Simultree is a short incremental game about monitoring life simulations.

$6.99

Microcosmum 2

A relaxing strategy game featuring unconventional gameplay. Your objectives include development, evolution, border expansion and protection of your…

$6.99

Hidden gems like Multicellular

Planetary Life

Terraform a barren world, tune its climate and watch the life you seed evolve across millennia, all at your own unhurried pace.

$11.99

Primordialis

Design a living creature from cells and send it into the deep, where every run rebuilds it from scratch.

$19.99

Cell Command

TURN-BASED TACTICS meets SNAKE: A new roguelike in the Genome Guardian universe.

$17.99

Pathogenic

You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your…

$9.99

Simultree

Simultree is a short incremental game about monitoring life simulations.

$6.99

Strange Seed

Eat DNA, grow new body parts and fight your way from forests to volcanoes as the build you design.

$14.99

ANLIFE: Motion-Learning Life Evolution

A relaxing evolution simulation where AI-driven block creatures move in unexpected ways.

$13.99

Nature & Life - Drunk On Nectar

Play as Animals, Live in Nature! Multiple game modes include Realistic Lifecycles, Survival, Sandbox, Fantasy and Exploration.

$14.99

Sipho

Sipho is an action survival game with an intricate building system. Grow your own creature and take over the local ecosystem.

$17.99

Creature Crafter

Design creatures from body parts, watch them come to life, and explore open worlds with friends.

$7.99

Ecosystem

Seed a simulated ocean with random creatures and watch evolution do the rest.

$19.99

Everything is Crab: The Animal Evolution Roguelite

Eat, grow and stitch together absurd animal abilities into a new chimera every run, in a fast and funny pixel ecosystem that keeps you on your toes.

$9.99

Newest games like Multicellular