Games like Pathogen

Hooked on the replayable and competitive side of Pathogen? Start with these games when you are ready.

Plague Inc: Evolved
You are Patient Zero's pathogen, and your job is to end human history. Plague Inc: Evolved is a tense strategy sim about spreading, mutating, and outsmarting cure labs, with 10 disease types, 23 scenarios, and endless custom plagues to try next.
Replayable, Competitive, Dark
94% of 59,983 Steam reviews are positivePlayers online now: 1,056$2.99
Pathogen-病原体
"Pathogen" is a STG game base on real human body with little Rogue-Like element. You can propagate evolve infect and hide as different kinds of pathogens in human body.
Replayable, Dark
78% of 18 Steam reviews are positive$6.99
COVID: The Outbreak
COVID: The Outbreak is a real-time strategy game in which you play the role of a global organization that has to deal with a global pandemic. Issue decrees, manage resources, develop projects, and construct buildings. A race for the vaccine begins!
Replayable, Dark
70% of 84 Steam reviews are positive$13.99
Pathogenic
You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your own, building a parasite that breaks the game. Colorful, squishy and hard, with runs that end and immediately demand another.
Replayable
93% of 5,173 Steam reviews are positivePlayers online now: 655$9.99
Quarantine
Quarantine is an intense turn-based strategy game about waging war on pandemic disease. Recruit a team of specialized operatives to deploy on worldwide missions. Research the contagion, upgrade your tech, and quarantine the outbreak before it kills us all.
Replayable, Dark
60% of 326 Steam reviews are positive$9.99
Be Coronavirus
A viral strategy game: You take the role of Coronavirus. With no interference from you, it will spread around the world, infect new places, evolve, mutate, and reshape the landscape of humanity… that is, it would, if it weren’t for other viruses, and medical interference, waiting to stop it.
Replayable, Competitive
100% of 2 Steam reviews are positive$3.99
Bio Inc. Classic
You are the disease in this biomedical strategy sim. Pick risk factors, stack more than 100 conditions across every body system, and stall the doctors before they cure your patient. With 18 stages, four difficulties and endless builds, it is grim, methodical and hard to put down.
Replayable, Dark
69% of 36 Steam reviews are positivePlayers online now: 1Free
Infection: Humanity's Last Gasp
Infection: Humanity's Last Gasp uses simple mechanics in a multitude of combinations to create engaging, deep gameplay as you try to eliminate an evolving virus that could spell the end of the human race.
Replayable, Dark
44% of 18 Steam reviews are positive$9.99
Infect and Destroy
Play as the zombies! Infect and Destroy is an indie game in which you play as an infectious disease with the sole purpose of eliminating everyone on Earth. Play as an ultra-intelligent self-aware virus capable of reanimating the dead and turning them into your minions.
Replayable, Dark
20% of 20 Steam reviews are positive$6.99
Bio Inc. Redemption
Play doctor or play plague. Bio Inc. Redemption is a biomedical strategy game where you either diagnose and save a dying patient or build the disease that kills them, one organ system at a time. Over 600 real conditions, tough real-time decisions, and a dark sense of humor.
Replayable, Dark
87% of 3,116 Steam reviews are positivePlayers online now: 32$12.99
Infectious
Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. Generate clones and watch them propagate, infecting cells and taking down bosses.
Replayable
65% of 79 Steam reviews are positive$3.99
Infectonator 3: Apocalypse
You are the bad guy here. Drop a virus on an unsuspecting town, watch panic spread, and splice DNA until your zombies go from shuffling biters to leaping monstrosities. A pixelart outbreak sim with dark humor, 35-plus undead to unlock, and a human race that is racing to cure you.
Replayable, Dark
83% of 1,273 Steam reviews are positivePlayers online now: 13$12.99

Cheaper than Pathogen

Plague Inc: Evolved

Spread a pathogen across the globe, mutate it faster than humanity can fight back, and watch your strategy play out differently every run.

$2.99

Be Coronavirus

A viral strategy game: You take the role of Coronavirus. With no interference from you, it will spread around the world, infect new places, evolve…

$3.99

Listeria Wars

Listeria Wars is a real-time tactical game. You defend against the pathogenic microbes, attacking an infected organism.

$5.90

Infectious

Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your…

$3.99

Micromanagement

You're bacteria. Luckily, you have psychic powers! Control your mutation to overwhelm and conquer.

$4.99

Pandemia: Virus Outbreak

2 in 1, Swipe cards to face the deadly virus threat in this story driven strategy game.

$0.99

Immunica

Become the immune system. Hover to kill. Weapons fire automatically.

$3.99

Propa.

In this RTS game, control your virus to replicate and evolve against a powerful immune system. Equip gene segments to create unique viral armies.

$4.87

Pandemic Crisis

In the event of a global pandemic, would your first priority be preserving lives or saving the economy?

$2.99

Pathogen: Survival

Pathogen: Survival is an arcadey wave based FPS zombie game that prioritises progression and customisation.

$4.99

Infectra

Ifectra is a strategy game set in 2124 on the distant planet Emevera III, ruled by the Maxploit Corporation, where an epidemic of a yet unknown…

$0.99

Infection

Virus is spreading in this world, try to survive as long as possible. Avoid other or try to approach and cure them?

$1.99

Hidden gems like Pathogen

Pathogenic

You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your…

$9.99

After Inc: Revival

Decades after the Necroa Virus, survivors climb out of their bunkers into a green, broken Britain.

$10.79

Welcome Back, Commander

Commander, your strike team is to dive deep into the contaminated city of Sun Stone and get some answers before the mysterious deadly plague spreads .

$14.99

Extinction Day

You are the end of the world. Seed plagues, storms, volcanoes and wars across a 3D globe, feed the destruction back into upgrades, and stack…

$14.99

Infectonator 3: Apocalypse

Spread a zombie virus across the globe, mutate your horde, and wipe out humanity before it finds a cure.

$12.99

Cepheus Protocol

Run the fight against a zombie plague in an open world, and take direct control of a soldier when the situation demands it.

$19.99

Bio Inc. Redemption

Diagnose a dying patient or engineer the disease that takes them down, one organ system at a time.

$12.99

Microcosmum: survival of cells

Grow your cells, absorb your rivals and take over the microscopic world, one drifting organism at a time.

$7.99

Pandemic Train

In Pandemic Train you are in charge of the crew aboard a train roaming the postapocalyptic wasteland, ravaged by both war and a deadly plague.

$16.99

Plague Inc: Evolved

Spread a pathogen across the globe, mutate it faster than humanity can fight back, and watch your strategy play out differently every run.

$2.99

Quarantine

Quarantine is an intense turn-based strategy game about waging war on pandemic disease.

$9.99

Pathogen-病原体

"Pathogen" is a STG game base on real human body with little Rogue-Like element.

$6.99

Newest games like Pathogen