Games like Isolate ME!

Remember how replayable and tense Isolate ME! felt at its best? These games keep things close enough to feel familiar.

COVID: The Outbreak
COVID: The Outbreak is a real-time strategy game in which you play the role of a global organization that has to deal with a global pandemic. Issue decrees, manage resources, develop projects, and construct buildings. A race for the vaccine begins!
Replayable, Tense, Dark
70% of 84 Steam reviews are positive$13.99
Self-Isolation
This game is a simulation of self-isolation. You need to support your family, not to lose your job and finally not to go crazy.
Replayable, Tense, Dark
85% of 418 Steam reviews are positive$4.99
40 Days [四十天]
40 Days is a special strategy simulation game related to infectious diseases spread all over the city. You, as ahead of the quarantine department, have been given full authority and manpower to contain the city, deal with different parties, virus in the city and most importantly find out the cure.
Replayable, Tense, Dark
33% of 9 Steam reviews are positive$4.99
Pandemic: The Virus Outbreak
Are you good enough to make your country overcome the pandemic? Try it out! You're the president of a new country, In 1/1/2020 a pandemic started and you have to manage the country balancing 8 constantly chaging statistics using isolation measures or budget investments.
Replayable, Dark
27% of 11 Steam reviews are positive$1.99
Isolation Story
VIRUS-19 has ravaged the world! Take control of a mindless citizen and live through a 7-day quarantine inside of Lockdown City.
Replayable, Dark
$9.99
Pandemic Isolation
In this game you have to help the main character to hold on in self-isolation with limited resources. Every day you face a difficult choice: how to eke out your groceries, whose request you should respond to, and who is to be left without a piece of bread.
Replayable, Dark
71% of 14 Steam reviews are positive$5.99
Quarantineer
For the glory of Motherland, the truth shall never be revealed. None of us expected this, Yet history is repeating itself.
Replayable, Tense, Retro
80% of 307 Steam reviews are positive$9.99
Quarantine: Global Pandemic
In Quarantine, you make the pandemic policies and funding priorities for your country as the head of the Health and Human Services Department. You will have to save your country from this global pandemic, while trying to keep the public and government officials happy...
Replayable
64% of 11 Steam reviews are positive$3.99
Covid Simulator
COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.
Replayable
80% of 61 Steam reviews are positive$4.99
Shyondemic
You play as a Husky Girl, Survive the Pandemic, make a story path for her. Move fast or Die fast.
Replayable, Tense, Retro
100% of 15 Steam reviews are positive$2.99
Infection Free Zone
Pick any real place on Earth, from your own street to a city across the ocean, and turn it into a survivor settlement after a virus empties the world. Scavenge familiar buildings by day, then hold your walls against fast, aggressive infected hordes every night. A colony sim with a map you already know.
Tense, Dark
80% of 16,807 Steam reviews are positivePlayers online now: 480$24.99
Quarantine Zone: The Last Check
Run the checkpoint in a city overrun by the dead. Scan survivors for bites, fevers and hidden contraband, decide who enters, who waits in quarantine and who goes to the lab, then keep your camp fed, powered and defended. Every stamp matters, and one slip lets the plague walk right through.
Replayable, Tense, Dark
81% of 12,661 Steam reviews are positivePlayers online now: 470$19.99

Cheaper than Isolate ME!

Pandemic: The Virus Outbreak

Are you good enough to make your country overcome the pandemic? Try it out!

$1.99

Pandemia: Virus Outbreak

2 in 1, Swipe cards to face the deadly virus threat in this story driven strategy game.

$0.99

Outbreak Story

Player acts as a state administrator to make decisions on epidemic prevention and then a mathematical model can simulate the impact of your decision.

$0.99

Vaccine

Vaccine is a Minesweeper-inspired roguelike where you use logic and limited medicine to cure the infected.

$1.99

Infection

Virus is spreading in this world, try to survive as long as possible. Avoid other or try to approach and cure them?

$1.99

Odenavirus Online

In this building that refuses to closes due to the pandemic, you are free to create your character, interact with other players, set up your room…

$1.99

Stayhome Simulator

The game will teach you how to stay at home, make trips to the store, use masks and various antiseptics. Buckwheat, toilet paper, masks, city pass..

$0.99

ISOLATE

You, who needed money, will participate in a secret biological experiment.

$1.99

Bright Days in Quarantine

In a world where you need to stay at home to curb a virus pandemic, get your act together by revisiting old hobbies and find joy in the small things…

$1.99

The HeartBeat

The Heartbeat is a lightweight political simulation game that incorporates rhythmic, text-oriented options.

$0.99

Putin kills: Coronavirus

Great showdown 2020: COVID-19 vs BIGCOCK-19

$0.99

the infected city a long way home

A story-driven survival horror game set during the first days of a zombie outbreak in Victor City.

$2.65

Hidden gems like Isolate ME!

Survivalist: Invisible Strain

Recruit strangers, build a camp and hold it together while an infected survivor hides in plain sight.

$11.99

Police Chief Simulator

Hire your officers, send out patrols and grow a small-town police department at your own calm pace.

$15.99

Welcome Back, Commander

Commander, your strike team is to dive deep into the contaminated city of Sun Stone and get some answers before the mysterious deadly plague spreads .

$7.79

Quarantine Zone: The Last Check

Scan the desperate, weigh each risk and hold the line at a checkpoint where one mistake lets the plague in.

$19.99

DeadOS

DeadOS is an early access zombie outbreak simulator by Benn Powell that focuses on city-wide scenarios where you have access to fully customize your…

$11.99

Quarantineer

For the glory of Motherland, the truth shall never be revealed. None of us expected this, Yet history is repeating itself.

$9.99

Self-Isolation

This game is a simulation of self-isolation. You need to support your family, not to lose your job and finally not to go crazy.

$4.99

Infection Free Zone

Build a survivor colony anywhere on the map, scavenge by day and fight off the infected when night falls.

$24.99

Police Officer

Police Officer is a first-person police station simulator where you manage a police station: process suspects, hear citizens' pleas, and manage the…

$11.99

112 Operator

Pick any city on the map, staff its emergency services and steer every patrol, ambulance and fire crew through a shift that never slows down.

$24.99

Cepheus Protocol

Run the fight against a zombie plague in an open world, and take direct control of a soldier when the situation demands it.

$19.99

Shelter Manager

We live in a troubled world. Viruses, military conflicts - you never know what danger the world will face tomorrow. It's time to get ready now!

$14.99

Newest games like Isolate ME!