Molecule - a chemical challenge
Discover molecules and learn about science in this addictive Sokoban-style puzzle game!
78% of 9 Steam reviews are positive$1.99
Games like Against the Gradient
Hooked on the minimalist and relaxing side of Against the Gradient? These games keep things close enough to feel familiar.
Cellchemist
Solve carefully crafted puzzles and experiment with over 100 cells in this physics sandbox where every pixel is simulated.
Minimalist, Relaxing
89% of 47 Steam reviews are positiveFreeCellula
Manage a colony of living cells in a strategy game built from real biology. Build phospholipid membranes, place organelles, import nutrients, fight viruses, detect cancer, and divide your cells to grow. No tutorials. No lectures. Learn by keeping the cell alive.
Minimalist, Relaxing
$6.99Little Cells
Launch colorful cells to create chains reactions and survive the microscopic chaos. Match colors to eliminate threat and cure this deadly infection before it spread.
Minimalist
81% of 16 Steam reviews are positive$3.99Tricone Lab
A unique abstract puzzle game with an emphasis on lateral thinking. Use catalysts to build compounds and manipulate cell structures. 100 puzzle levels and a level editor to create your own custom puzzle designs.
Minimalist, Relaxing
93% of 27 Steam reviews are positive$9.99胞-胞实验室 Cell-Cell Lab
Cell-Cell Lab is a grid-based puzzle game! Fangfang, a cell born from a secret experiment, will use its unique fusion ability to cooperate with other cells, overcome numerous obstacles, and complete this unknown experiment.
Relaxing
100% of 3 Steam reviews are positive$2.99TransPlan
Deliver a payload from point A to point B with only a few simple tools and the laws of physics. Create ramps and catapults, watch objects tumble and fall, and someway... somehow reach the destination. Each project is a hand-drawn puzzle for you to interact with -- Devise a plan, experiment, and make it happen!
Minimalist, Relaxing
91% of 175 Steam reviews are positive$2.99Prime Mover
Retrace the path of the Prime Mover to uncover the story of the Byte of Burden! Prime Mover is an open-ended puzzle game about designing circuit boards.
Minimalist, Relaxing
87% of 179 Steam reviews are positive$14.99Microcosmum: survival of cells
A real-time strategy about microorganisms, played out in a calm, colorful microscopic world. Send your cells drifting across the level, absorb weaker neighbors and grow, and outmaneuver every rival on the board. Simple to learn, oddly soothing, and surprisingly tactical once the field fills up.
Minimalist, Relaxing
80% of 1,119 Steam reviews are positivePlayers online now: 1$7.99CHR$(143)
A rich and challenging physics-based puzzle /logic /construction /programming game! Master ballistics, fluid mechanics, thermodynamics, chemical and nuclear reactions, use automation bricks, build structures, machines, vehicles, produce power, solve puzzles, pierce the fog and defeat CHR$!
Minimalist, Relaxing
96% of 75 Steam reviews are positive$7.99Contraption Maker
The spiritual successor to The Incredible Machine, from its original designer. Chain together bowling balls, lasers, mice and balloons to pop, feed and launch your way through hundreds of puzzles, then build your own contraptions and share them. Physics that always behave, puzzles that gently ramp up, and a workshop full of machines other people dreamed up.
Relaxing
92% of 923 Steam reviews are positivePlayers online now: 20$12.99Life on the Edge
Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!
Minimalist
88% of 102 Steam reviews are positiveFreeRailbound
A cozy track-bending puzzle game about two dogs riding a train around the world. Lay rails, flip switches and time barriers so every carriage hooks up to the locomotive in the right order. Over 240 puzzles, a level editor, and art and music that stay friendly even when the puzzles stop being polite.
Minimalist, Relaxing
94% of 1,833 Steam reviews are positivePlayers online now: 5$12.99
Cheaper than Against the Gradient
Bacteria
'Bacteria' - A relaxing puzzle game based on the rules of the cellular automaton ‘Life’ devised by John Horton Conway in 1970.
62% of 119 Steam reviews are positivePlayers online now: 2$0.99
trappuzzler
trappuzzler is a puzzle game about feeling trapped and moving people.
100% of 4 Steam reviews are positive$1.99
Charge!
Charge is a level-based puzzle game where you control the flow of charge around a circuit board.
100% of 5 Steam reviews are positive$1.99
Infection
Infection is a relaxing and minimal puzzle game. Infect all the cells by virus to get success in each level.
100% of 8 Steam reviews are positive$0.99
Entropy Rising
Entropy Rising is a first-person physics-based puzzle game set in a weird world filled with mysterious flying orbs and oversized measurement devices.
57% of 30 Steam reviews are positive$0.99
The Envolution Of Wandaland
A minimal puzzle game, combine the cells and then piece together various creatures
100% of 2 Steam reviews are positive$0.99
Art Of Gravity
Art Of Gravity is a voxel/physics based puzzle game, revolving around the theme of destroying abstract figures, which results in mesmerizing…
91% of 601 Steam reviews are positive$1.99
Tiny Bridge: Ratventure
This mind-bending game will challenge you to create complex structures to get your woodland creatures over vast chasms.
63% of 819 Steam reviews are positive$1.99
Please Fix The Road
Please Fix The Road is a colorful, minimalistic, laid-back and casual puzzle game in which it's probably not hard to guess... you're fixing roads!
77% of 263 Steam reviews are positive$1.99
Awesome Machine
This is a "Rube Goldberg" style puzzle game inspired on the award winning "The incredible Machine".
43% of 14 Steam reviews are positive$1.99
Hidden gems like Against the Gradient
Gentoo Rescue
A puzzler about sliding penguins and walruses. Pick up items to push, pull, bounce, swap, stop, steal, or explode.
99% of 246 Steam reviews are positivePlayers online now: 3$19.99
Railbound
A cozy track-bending puzzle game about two dogs riding a train around the world.
94% of 1,833 Steam reviews are positivePlayers online now: 5$12.99
Thrive
Grow a microbe into a species, choosing every adaptation as your alien world changes around you.
92% of 1,726 Steam reviews are positivePlayers online now: 21$4.99
Lifecraft
Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its…
81% of 141 Steam reviews are positive$22.99
Life on the Edge
Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus.
88% of 102 Steam reviews are positiveFree
Active Neurons - Wonders Of The World
A puzzle slasher that trains spatial and logical thinking. Power up your brains!
93% of 210 Steam reviews are positiveFree
MOLEK-SYNTEZ
Use the MOLEK-SYNTEZ to create small molecules with various pharmacological effects from the comfort of your small Romanian apartment.
91% of 528 Steam reviews are positive$9.99
Prime Mover
Retrace the path of the Prime Mover to uncover the story of the Byte of Burden!
87% of 179 Steam reviews are positive$14.99
Opus Magnum
Program alchemical arms on a hex grid and build machines that work any way you like.
97% of 6,120 Steam reviews are positivePlayers online now: 181$19.99
Bridge Constructor Portal
Build test tracks through the Aperture labs, mix in portals and gels, and see if your contraptions survive their first crossing.
91% of 6,714 Steam reviews are positivePlayers online now: 41$9.99
TransPlan
Deliver a payload from point A to point B with only a few simple tools and the laws of physics.
91% of 175 Steam reviews are positive$2.99
Sokobond
Sokobond is an elegantly designed puzzle game about chemistry. It's logical, minimalist, and beautiful - crafted with love and science.
93% of 548 Steam reviews are positivePlayers online now: 2$14.99
Newest games like Against the Gradient
U.V.S. Nirmana
U.V.S. Nirmana is a engineering puzzle game from Coincidence, the creators of Kaizen: A Factory Story and the inventors of the Zach-like.
88% of 228 Steam reviews are positivePlayers online now: 1$14.99
Cellchemist
Solve carefully crafted puzzles and experiment with over 100 cells in this physics sandbox where every pixel is simulated.
89% of 47 Steam reviews are positiveFree
胞-胞实验室 Cell-Cell Lab
Cell-Cell Lab is a grid-based puzzle game! Fangfang, a cell born from a secret experiment, will use its unique fusion ability to cooperate with…
100% of 3 Steam reviews are positive$2.99
Aggi's Tiny Friends
Join Aggi and dive into a world that lies just out of sight. Customize your own cell and see it thrive in a vibrant ecosystem.
100% of 3 Steam reviews are positive$4.99
Gentoo Rescue
A puzzler about sliding penguins and walruses. Pick up items to push, pull, bounce, swap, stop, steal, or explode.
99% of 246 Steam reviews are positivePlayers online now: 3$19.99
Lifecraft
Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its…
81% of 141 Steam reviews are positive$22.99
Boing Odyssey
Build contraptions with various tools to end all roasted chickens rightly in this physics puzzle game, or create and share your own challenges!
100% of 12 Steam reviews are positive$4.99
HYNPYTOL
They're coming. There's no hope. Still, you're a HYNPYTOL.
98% of 65 Steam reviews are positive$14.99
The Envolution Of Wandaland
A minimal puzzle game, combine the cells and then piece together various creatures
100% of 2 Steam reviews are positive$0.99
Can of Wormholes
Push, slice, ingest, flip, and squish worms in this puzzle game in which you play as a little sentient tin can.
99% of 572 Steam reviews are positivePlayers online now: 2$19.99
Railbound
A cozy track-bending puzzle game about two dogs riding a train around the world.
94% of 1,833 Steam reviews are positivePlayers online now: 5$12.99