Genome Guardian 2
Build a nanobot from hundreds of parts, splice DNA into hybrid bioweapons and blast through short, frantic runs in a neon-lit deep sea.
94% of 530 Steam reviews are positivePlayers online now: 11$15.99
Games like Active Immunity
If the replayable and fast-paced rhythm of Active Immunity stuck with you, this helps. These games keep things close enough to feel familiar.
Pathogenic
You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your own, building a parasite that breaks the game. Colorful, squishy and hard, with runs that end and immediately demand another.
Also in Co-op · Replayable, Fast-paced, Tense
93% of 5,160 Steam reviews are positivePlayers online now: 655$9.99Supre-Immune
Join a roguelike action where cute immune cells battle viruses. Collect data in fast-paced combat, gain weapons and abilities through evolution, or level up to grow stronger. The fun of building your own super immune cell with different combinations each run is up to you!
Replayable, Fast-paced, Tense
91% of 11 Steam reviews are positive$6.99A Way To Die
Enter the human body with A Way To Die! Play as a disease that attempts to infect its host by contaminating organs and mutating! Discover new ways to win every time you play with all the different diseases!
Replayable, Fast-paced, Tense
93% of 14 Steam reviews are positive$6.31BODYguard: CellWars
Take control of the body’s defense system in this fast-paced action shooter. Step into the role of a powerful immune cell and use precise touch controls to target and eliminate waves of invading bacteria and viruses.
Replayable, Fast-paced, Tense
100% of 2 Steam reviews are positive$2.99Immune Response
An exciting twin-stick shooter with a progressively increasing difficulty. Fight waves of pathogenic enemies, face difficult boss fights and survive for as long as you can!
Replayable, Fast-paced, Tense
$5.59Survivor Cells
Discover the beauty and fragility of life in Survivor Cells, a unique survival game against viruses and bacteria, which strategically combines the elements of roguelite, bullet hell and tower defense in a challenging experience. Your destiny depends on your agility and choices. How far will you get?
Replayable, Fast-paced, Tense
76% of 38 Steam reviews are positive$9.99Super Infection Massive Pathology
Guide a brave bacteria to rescue his fiancée Zoe from the creatures of the immune system, using an arsenal of organic weapons and unique abilities.
Replayable, Fast-paced, Tense
87% of 15 Steam reviews are positive$9.99Immunica
Become the immune system. Hover to kill. Weapons fire automatically. Manage your research lab, hire scientists, and develop a vaccine while fighting off endless pathogen hordes.
Replayable, Minimalist
72% of 46 Steam reviews are positive$3.99Infectious
Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. Generate clones and watch them propagate, infecting cells and taking down bosses.
Replayable, Fast-paced, Tense
65% of 79 Steam reviews are positive$3.99Immunity Protocol
Pilot an immune-cell sentinel in a neon pixel-art horde-survival auto-shooter. Move manually, auto-fire evolving weapons, draft upgrades, equip symbiotes, and survive escalating pathogen swarms inside a collapsing biotech system.
Replayable, Fast-paced, Tense
$5.99Immunity Tales
The tale of a group of immune cells around the body full of fights against several micro-organisms, challenges and puzzles will keep you glued to the screen until the end of the game.
Colorful
$0.99Systematic Immunity
Systematic Immunity is a challenging precision platformer set inside the human body...and not a particularly healthy one either. This body has been infected by a big, nasty bugger of a germ, who is making it his business to spawn many more germs as fast as he can.
Fast-paced, Tense, Minimalist
71% of 7 Steam reviews are positive$3.99
Hidden gems like Active Immunity
Funguys Swarm
Move through swarming flames, let your weapons fire themselves and stack upgrades into absurd screen-clearing builds.
89% of 1,130 Steam reviews are positivePlayers online now: 13$9.99
Pathogenic
You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your…
93% of 5,160 Steam reviews are positivePlayers online now: 655$9.99
Genome Guardian
COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth.
92% of 715 Steam reviews are positivePlayers online now: 4$11.99
Deflector
Deflector is a top down action rogue-lite set in a deadly microcosm. Dive deep into hostile worlds teeming with viruses.
87% of 280 Steam reviews are positivePlayers online now: 1$19.99
Infected Shelter
Infected Shelter is an ultra-violent rogue-lite post-apocalyptic beat'em up. Singleplayer and co-op for up to four players.
85% of 542 Steam reviews are positiveFree
HyperParasite
A rogue-lite twin-stick shooter/brawler that never plays the same twice.
83% of 100 Steam reviews are positive$17.99
REMEDIUM: Sentinels
Become a Sentinel and face the plague in roguelite fast-paced auto-shooter set in the same world as REMEDIUM game.
66% of 197 Steam reviews are positive$4.99
Defend Your Life: TD
Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria.
82% of 574 Steam reviews are positivePlayers online now: 2$9.99
Supre-Immune
Join a roguelike action where cute immune cells battle viruses.
91% of 11 Steam reviews are positive$6.99
A Way To Die
Enter the human body with A Way To Die! Play as a disease that attempts to infect its host by contaminating organs and mutating!
93% of 14 Steam reviews are positive$6.31
Newest games like Active Immunity
Genome Guardian 2
Build a nanobot from hundreds of parts, splice DNA into hybrid bioweapons and blast through short, frantic runs in a neon-lit deep sea.
94% of 530 Steam reviews are positivePlayers online now: 11$15.99
Funguys Swarm
Move through swarming flames, let your weapons fire themselves and stack upgrades into absurd screen-clearing builds.
89% of 1,130 Steam reviews are positivePlayers online now: 13$9.99
Ground Zero Hero
Kill mutants. Absorb their remains. Mutate into something stronger every run.
79% of 61 Steam reviews are positive$9.99
Pathogenic
You are the disease. Pathogenic is a fast roguelike shooter set inside a human body: hunt cells, rip out their organelles and graft them onto your…
93% of 5,160 Steam reviews are positivePlayers online now: 655$9.99
Supre-Immune
Join a roguelike action where cute immune cells battle viruses.
91% of 11 Steam reviews are positive$6.99
Immunica
Become the immune system. Hover to kill. Weapons fire automatically.
72% of 46 Steam reviews are positive$3.99
Going Viral
An infection has struck the body! As the mighty T-Cell, it's your duty to eradicate the invading pathogens!
100% of 3 Steam reviews are positive$1.99
Blasteria
A 2.5D Abstract Sci-Fi top-down shooter about decimating germs on a petri dish. Fill the screen with lasers to decimate hundreds of duplicating germs.
100% of 8 Steam reviews are positiveFree
Lone Survivors
An objective-driven bullet heaven where twelve classes build absurd weapon synergies across shifting fantasy biomes.
88% of 24 Steam reviews are positive$4.99
COVID-29
A third person, action-adventure game with a medieval and biology style.
100% of 3 Steam reviews are positive$3.99
BODYguard: CellWars
Take control of the body’s defense system in this fast-paced action shooter.
100% of 2 Steam reviews are positive$2.99
Super Infection Massive Pathology
Guide a brave bacteria to rescue his fiancée Zoe from the creatures of the immune system, using an arsenal of organic weapons and unique abilities.
87% of 15 Steam reviews are positive$9.99